TSPY-Like 2 antibody (AA 1-50)

Catalog No. ABIN7455002

This anti-TSPY-Like 2 antibody is a Rabbit Polyclonal antibody detecting TSPY-Like 2 in WB, IP and IHC (fp). Suitable for Human.

Quick Overview for TSPY-Like 2 antibody (AA 1-50) (ABIN7455002)

Target: TSPY-Like 2 (TSPYL2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPY-Like 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-TSPY-Like 2 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-DENTT Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TSPY-Like 2

Target: TSPY-Like 2 (TSPYL2)

Alternative Name: DENTT

Background: Background: Differentially-expressed nucleolar TGF-beta1 target protein (DENTT) is part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. DENTT may inhibit cell proliferation by inducing p53-dependent CDKN1A expression [taken from the Universal Protein Resource (UniProt) Q9H2G4].

Gene ID: 64061

NCBI Accession: NP_071400

UniProt: Q9H2G4

Pathways: ER-Nucleus Signaling