ICAM-3/CD50 antibody (AA 497-547)

Catalog No. ABIN7455023

This anti-ICAM-3/CD50 antibody is a Rabbit Polyclonal antibody detecting ICAM-3/CD50 in WB, IP and IHC (fp). Suitable for Human.

Quick Overview for ICAM-3/CD50 antibody (AA 497-547) (ABIN7455023)

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICAM-3/CD50 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-ICAM-3/CD50 Antibody

Binding Specificity: AA 497-547

Purpose: Rabbit anti-ICAM-3 Antibody, Affinity Purified

Predicted Reactivity: Chimpanzee

Purification: Affinity Purified

Immunogen: Between AA 497 and 547

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ICAM-3/CD50

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Alternative Name: ICAM-3

Background: Background: ICAM-3 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule [taken from NCBI Entrez Gene (Gene ID: 3385)].

Gene ID: 3385

NCBI Accession: NP_002153

UniProt: P32942