MVP antibody (AA 1-50)

Catalog No. ABIN7455064

The Rabbit Polyclonal anti-MVP antibody has been validated for WB, IP and IHC (fp). It is suitable to detect MVP in samples from Human.

Quick Overview for MVP antibody (AA 1-50) (ABIN7455064)

Target: MVP (Major Vault Protein (MVP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MVP antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-MVP Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-MVP/Major Vault Protein Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MVP

Target: MVP (Major Vault Protein (MVP))

Alternative Name: MVP/Major Vault Protein

Background: Background: Major Vault Protein (MVP) is the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport and may act as scaffolds for proteins involved in signal transduction. The encoded protein, also known as lung resistance-related protein (LRP), plays a role in multidrug resistance and expression of this gene may be a prognostic marker for several types of cancer [taken from NCBI Entrez Gene (Gene ID: 9961)].

Gene ID: 9961

UniProt: Q14764