TPR antibody (C-Term)

Catalog No. ABIN7455083

This anti-TPR antibody is a Rabbit Polyclonal antibody detecting TPR in WB, IP, ICC and IHC (fp). Suitable for Human.

Quick Overview for TPR antibody (C-Term) (ABIN7455083)

Target: TPR (Nucleoprotein TPR (TPR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPR antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-TPR Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-TPR Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 2300 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

ICC: 1:25 - 1:250. Formaldehyde fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells.

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TPR

Target: TPR (Nucleoprotein TPR (TPR))

Alternative Name: TPR

Background: Background: TPR (translocated promoter region) was identified in oncogenic fusions with the kinase domains of trk, met, and raf protooncogenes. TPR has also been identified as a candidate nuclear skeletal protein that localizes to nuclear pore-associated intranuclear filaments. TPR is part of an interchromasomal channel-based nuclear matrix that provides connectivity between the nuclear interior and periphery. It is implicated in intranuclear transport and export of mRNA and proteins.

Gene ID: 7175

NCBI Accession: NP_003283

UniProt: P12270