SASH1 antibody (AA 750-800)

Catalog No. ABIN7455238

The Rabbit Polyclonal anti-SASH1 antibody has been validated for WB, IF (p), IP and IHC (fp). It is suitable to detect SASH1 in samples from Human.

Quick Overview for SASH1 antibody (AA 750-800) (ABIN7455238)

Target: SASH1 (SAM and SH3 Domain Containing 1 (SASH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SASH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-SASH1 Antibody

Binding Specificity: AA 750-800

Purpose: Rabbit anti-SASH1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 750 and 800

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:250 - 1:1,000

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 3 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-SASH1 antibody A302-265A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SASH1

Target: SASH1 (SAM and SH3 Domain Containing 1 (SASH1))

Alternative Name: SASH1

Background: Background: SASH1 (SAM and SH3 domain containing 1) was identified in an in silico analysis of loss of heterozygosity (LOH) to identify genes downregulated in breast cancer. Since this discovery, it has also been found to be a candidate tumor suppressor in colon cancer. Structurally, SASH1 contains two SAM (sterile alpha motif) domains and one SH3 domain indicating a role in signal transduction and as a signaling adapter.

Gene ID: 23328

NCBI Accession: NP_056093

UniProt: O94885