SASH1 antibody (AA 1-300)

Catalog No. ABIN7270141

This Rabbit Polyclonal antibody specifically detects SASH1 in WB. It exhibits reactivity toward Human.

Quick Overview for SASH1 antibody (AA 1-300) (ABIN7270141)

Target: SASH1 (SAM and SH3 Domain Containing 1 (SASH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SASH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SASH1 Antibody

Binding Specificity: AA 1-300

Purpose: SASH1 Rabbit pAb

Sequence: MEDAGAAGPG PEPEPEPEPE PEPAPEPEPE PKPGAGTSEA FSRLWTDVMG ILDGSLGNID DLAQQYADYY NTCFSDVCER MEELRKRRVS QDLEVEKPDA SPTSLQLRSQ IEESLGFCSA VSTPEVERKN PLHKSNSEDS SVGKGDWKKK NKYFWQNFRK NQKGIMRQTS KGEDVGYVAS EITMSDEERI QLMMMVKEKM ITIEEALARL KEYEAQHRQS AALDPADWPD GSYPTFDGSS NCNSREQSDD ETEESVKFKR LHKLVNSTRR VRKKLIRVEE MKKPSTEGGE EHVFENSPVL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SASH1 (NP_056093.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SASH1

Target: SASH1 (SAM and SH3 Domain Containing 1 (SASH1))

Alternative Name: SASH1

Background: This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016],SASH1,SH3D6A,dJ323M4.1,dJ323M4,Cancer,Tumor suppressors,SASH1

Molecular Weight: 136kDa

Gene ID: 23328

UniProt: O94885