NEFL
Reactivity: Pig
WB, IF
Host: Mouse
Monoclonal
DA2
unconjugated
Application Notes
ELISA 1:5000-10000
Restrictions
For Research Use only
Format
Liquid
Storage
-20 °C,-80 °C
Storage Comment
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Expiry Date
12 months
Target
NEFL
(Neurofilament, Light Polypeptide (NEFL))
Alternative Name
NEFL
Background
CMT1F, CMT2E, CMTDIG, NF-L, NF68, NFL, PPP1R110 Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.