PDCD1LG2 antibody (APC)
Quick Overview for PDCD1LG2 antibody (APC) (ABIN7456517)
Target
See all PDCD1LG2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Isotype
- IgG2a, kappa
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Application Notes
- The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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Comment
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Matching Isotype Control: APC Mouse IgG2a, κ Isotype Control (ABIN7469779)
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
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Alternative Name
- CD273/PD-L2
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Background
- B7DC, CD273, PDCD1L2, PDL2,CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.
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Gene ID
- 80380
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UniProt
- Q9BQ51
Target
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