CD163 antibody (APC)

Catalog No. ABIN7456603

The Rat Monoclonal anti-CD163 antibody has been validated for FACS. It is suitable to detect CD163 in samples from Mouse.

Quick Overview for CD163 antibody (APC) (ABIN7456603)

Target: CD163

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD163 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: S15049F

Product Details anti-CD163 Antibody (APC)

Isotype: IgG2a, kappa

Application Details

Application Notes: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Comment:

Matching Isotype Control: APC Rat IgG2a, κ Isotype Control[2A3] (ABIN7469841)

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % Protein protectant

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD163

Target: CD163

Alternative Name: CD163

Background: M130, MM130, SCARI1,CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

Gene ID: 93671

UniProt: Q2VLH6