CD161 antibody (APC)

Catalog No. ABIN7456608

This Mouse Monoclonal antibody specifically detects CD161 in FACS. It exhibits reactivity toward Rat.

Quick Overview for CD161 antibody (APC) (ABIN7456608)

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD161 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: 3-2-3

Product Details anti-CD161 Antibody (APC)

Isotype: IgG1, kappa

Application Details

Application Notes: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: APC Mouse IgG1, κ Isotype Control[MOPC-21] (ABIN7469762)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % Protein protectant

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD161

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Alternative Name: CD161

Background: NKR-P1, CD161a/CD161b, NKR-P1a/KLRB1a,CD161 is a 30 kD type II transmembrane C-type lectin, expressed as a homodimer. Rat NKR-P1 receptors are primarily expressed on NK cells, a subset of T cells, dendritic cells, and activated monocytes. There are three different types of NKR-P in rat, namely NKR-P1a, NKR-P1b, and NKR-P1c. NKR-P1a does not contain an ITIM structure and is an activating receptor, while NKR-P1b contains an ITIM and displays inhibitory function. LLT-1 (ligand lectin like transcript 1) is the ligand, while KLR (killer cell lectin like) functions as a receptor.

Gene ID: 362443

UniProt: P27471, A4KWA1, Q5NKN4, Q5NKN2