ITGAL antibody (Biotin)
Quick Overview for ITGAL antibody (Biotin) (ABIN7456643)
Target
See all ITGAL AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Isotype
- IgG1, kappa
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Application Notes
- For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
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Comment
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Matching Isotype Control: Biotin Mouse Rat IgG1, κ Isotype Control (ABIN7469769)
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2~8°C. Do not freeze.
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- ITGAL (Integrin alpha-L (ITGAL))
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Alternative Name
- CD11a
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Background
- Integrin alpha-L,Itgal,CD11 antigen-like family member A,LFA-1A,Lymphocyte antigen 15,Ly-15,CD11a,CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
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Gene ID
- 3683
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UniProt
- P20701
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Pathways
- Activated T Cell Proliferation, Integrin Complex
Target
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