IL-4 antibody (FITC)

Catalog No. ABIN7456895

This anti-IL-4 antibody is a Rat Monoclonal antibody detecting IL-4 in ICFC. Suitable for Human.

Quick Overview for IL-4 antibody (FITC) (ABIN7456895)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-4 antibody is conjugated to FITC

Application: Intracellular Flow Cytometry (ICFC)

Clone: MP4-25D2

Product Details anti-IL-4 Antibody (FITC)

Isotype: IgG1, kappa

Application Details

Application Notes: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: FITC Rat IgG1, κ Isotype Control (ABIN7469811)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL-4

Background: Interleukin-4,IL-4,B-cell IgG differentiation factor,B-cell growth factor 1,BSF-1,IGG1 induction factor,IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.

Gene ID: 3565

UniProt: P05112

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation