CD44 antibody (PE)

Catalog No. ABIN7457161

The Rat Monoclonal anti-CD44 antibody has been validated for FACS. It is suitable to detect CD44 in samples from Human.

Quick Overview for CD44 antibody (PE) (ABIN7457161)

Target: CD44

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This CD44 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: Hermes-1

Product Details anti-CD44 Antibody (PE)

Isotype: IgG2a, kappa

Application Details

Application Notes: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: PE Rat IgG2a, κ Isotype Control (ABIN7469829)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD44

Target: CD44

Alternative Name: CD44

Background: LHR,PGP-I,CDw44,Epican,HUTCH-I,CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Gene ID: 960

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling