IFNGR1 antibody

Catalog No. ABIN7457947

The Rat Monoclonal anti-IFNGR1 antibody has been validated for FACS. It is suitable to detect IFNGR1 in samples from Mouse.

Quick Overview for IFNGR1 antibody (ABIN7457947)

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IFNGR1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: GR-20

Product Details anti-IFNGR1 Antibody

Purification: Purified

Sterility: 0.2 μm filtered

Endotoxin Level: Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Matching Isotype Control: AF/LE Purified Rat IgG2a, κ Isotype Control (ABIN7469836)

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store at 2~8°C. Do not freeze.

Target Details for IFNGR1

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Alternative Name: CD119

Background: Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119,CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Gene ID: 15979

UniProt: P15261

Pathways: Interferon-gamma Pathway