Phone:: +1 877 302 8632
Fax:: +1 888 205 9894 (Toll-free)
E-Mail:: orders@antibodies-online.com

For best experience we recommend to activate Javascript in your browser.

PD-L1 antibody

This Rat Monoclonal antibody specifically detects PD-L1 in FACS and BR. It exhibits reactivity toward Mouse.

Catalog No. ABIN7457961

Quick Overview for PD-L1 antibody (ABIN7457961)

Target

See all PD-L1 Antibodies

PD-L1 (CD274 (PD-L1))

Reactivity

274
141
72
6
6
5
5
1
1

Mouse

Host

154
145
19
5
4
4
2
1

Rat

Clonality

Monoclonal

Conjugate

This PD-L1 antibody is un-conjugated

Application

194
145
95
74
45
45
44
40
28
15
11
10
7
7
4
3
3
2
2
1
1
1
1
1
1

Flow Cytometry (FACS), Blocking Reagent (BR)

Clone

10F-9G2

Discover our top product PD-L1 Primary Antibody

Purification

Purified

Sterility

0.2 μm filtered

Endotoxin Level

Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotype

IgG2b, kappa
anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 Reactivity: Human WB, FACS, ELISA, IF Host: Goat Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Mouse Monoclonal 9B5F4 unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 Reactivity: Human FACS, IHC, ELISA Host: Mouse Monoclonal 6D9A2 unconjugated

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 Reactivity: Human, Mouse WB, FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 Reactivity: Human WB, FACS, IF, ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-234) antibody
PD-L1 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Comment

Matching Isotype Control: AF/LE Purified Rat IgG2b, κ Isotype Control (ABIN7469855)

Restrictions

For Research Use only
Concentration

0.5 mg/mL

Buffer

PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

Preservative

Azide free

Storage

4 °C

Storage Comment

Store at 2~8°C. Do not freeze.
Target

PD-L1 (CD274 (PD-L1))

Alternative Name

CD274/PD-L1

Background

B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.

Gene ID

60533

UniProt

Q9EP73

Pathways

Cancer Immune Checkpoints

You are here: