ADA antibody (AA 65-170) (Biotin)

Catalog No. ABIN719473

This Rabbit Polyclonal antibody specifically detects ADA in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for ADA antibody (AA 65-170) (Biotin) (ABIN719473)

Target: ADA (Adenosine Deaminase (ADA))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADA antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ADA Antibody (Biotin)

Binding Specificity: AA 65-170

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Adenosine deaminase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ADA

Target: ADA (Adenosine Deaminase (ADA))

Alternative Name: Adenosine deaminase

Background:

Synonyms: Adenosine deaminase, Adenosine aminohydrolase, ADA, ADA1

Background: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.

Gene ID: 100

UniProt: P00813

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process