THOC1 antibody (AA 15-374)

Catalog No. ABIN7464128

This anti-THOC1 antibody is a Mouse Monoclonal antibody detecting THOC1 in WB, IHC, IF, IP, IHC (p), ICC and ChIP. Suitable for Human.

Quick Overview for THOC1 antibody (AA 15-374) (ABIN7464128)

Target: THOC1 (THO Complex 1 (THOC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This THOC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP)

Grade: KO Validated

Clone: 5-00E-10

Product Details anti-THOC1 Antibody

Binding Specificity: AA 15-374

Specificity: Knockdown/Knockout validation was supported by references (PMID:25296641)

Cross-Reactivity: Hamster, Human, Monkey, Mouse, Rat

Purification: Protein G purified

Immunogen: Amino acids 15-374 of human p84 expressed in E. coli.

Isotype: IgG2b

Application Details

Application Notes: WB: 0.3 - 2 μg/mL. ICC/IF: 0.5 - 2 μg/mL. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2 , A375 , HeLa nucleus , NIH-3T3 , mouse brain , PC-12 , mouse Cerebellum

Validation: KO/KD, Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for THOC1

Target: THOC1 (THO Complex 1 (THOC1))

Alternative Name: THO complex 1

Background: THO complex 1 , HPR1 , P84 , P84N5,HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).[supplied by OMIM, Nov 2010]

Molecular Weight: 76 kDa

Gene ID: 9984

UniProt: Q96FV9