FIP200 antibody (C-Term)

Catalog No. ABIN7464138

This Rabbit Polyclonal antibody specifically detects FIP200 in WB. It exhibits reactivity toward Human.

Quick Overview for FIP200 antibody (C-Term) (ABIN7464138)

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FIP200 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FIP200 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human FIP200. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2 , human RB1CC1-transfected 293T cells

Validation: Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FIP200

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Alternative Name: RB1 inducible coiled-coil 1

Background: RB1 inducible coiled-coil 1 , ATG17 , CC1 , FIP200 , PPP1R131,The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]

Molecular Weight: 183 kDa

Gene ID: 9821

UniProt: Q8TDY2

Pathways: Regulation of Cell Size, Autophagy