ADAR antibody

Catalog No. ABIN7464281

This anti-ADAR antibody is a Mouse Monoclonal antibody detecting ADAR in WB, IF, IP and ICC. Suitable for Human.

Quick Overview for ADAR antibody (ABIN7464281)

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADAR antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Grade: KO Validated

Clone: GT1066

Product Details anti-ADAR Antibody

Cross-Reactivity: Human

Purification: Affinity purified by Protein G.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ADAR1. The exact sequence is proprietary.

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ADAR

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Alternative Name: adenosine deaminase RNA specific

Background: Adenosine deaminase RNA specific , ADAR1 , AGS6 , DRADA , DSH , DSRAD , G1P1 , IFI-4 , IFI4 , K88DSRBP , P136,This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Molecular Weight: 136 kDa

Gene ID: 103

UniProt: P55265

Pathways: Protein targeting to Nucleus