HIST1H4A antibody (acLys8)

Catalog No. ABIN7464450

This Mouse Monoclonal antibody specifically detects HIST1H4A in WB, IF, ICC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for HIST1H4A antibody (acLys8) (ABIN7464450)

Target: HIST1H4A (Histone Cluster 1, H4a (HIST1H4A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HIST1H4A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GT478

Product Details anti-HIST1H4A Antibody

Binding Specificity: acLys8

Cross-Reactivity: Human, Mouse, Rat

Purification: Affinity purified by Protein G.

Immunogen: Carrier-protein conjugated synthetic peptide surrounding acetyl Lys8 of human Histone H4. The exact sequence is proprietary.

Isotype: IgG3

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa , HeLa (0.4μM Trichostatin A for 18 hr)

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.95 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HIST1H4A

Target: HIST1H4A (Histone Cluster 1, H4a (HIST1H4A))

Alternative Name: histone cluster 1, H4a

Background: H4FA antibody , HIST1H4A antibody , Histone H4 antibody , Histone H4K8ac (acetyl Lys8) antibody [GT478] antibody , histone cluster 1, H4a antibody,Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq]

Molecular Weight: 11 kDa

Gene ID: 8359