ACADSB antibody

Catalog No. ABIN7464556

The Rabbit Polyclonal anti-ACADSB antibody has been validated for WB, IF, ICC and IHC (p). It is suitable to detect ACADSB in samples from Human.

Quick Overview for ACADSB antibody (ABIN7464556)

Target: ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACADSB antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ACADSB Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ACADSB. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:5000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2 , ACADSB-transfected 293T

Validation: Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ACADSB

Target: ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))

Alternative Name: acyl-CoA dehydrogenase short/branched chain

Background: Acyl-CoA dehydrogenase short/branched chain , 2-MEBCAD , ACAD7 , SBCAD,Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa. [provided by RefSeq]

Molecular Weight: 47 kDa

Gene ID: 36

UniProt: P45954

Pathways: Monocarboxylic Acid Catabolic Process