APOC1 antibody

Catalog No. ABIN7464622

The Rabbit Polyclonal anti-APOC1 antibody is suitable to detect APOC1 in samples from Human. It has been validated for WB.

Quick Overview for APOC1 antibody (ABIN7464622)

Target: APOC1 (Apolipoprotein C-I (APOC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APOC1 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length Apolipoprotein CI human recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: human plasma , APOC1-transfected 293T

Validation: Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for APOC1

Target: APOC1 (Apolipoprotein C-I (APOC1))

Alternative Name: apolipoprotein C1

Background: Apolipoprotein C1 , Apo-CI , ApoC-I , apo-CIB , apoC-IB,This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016]

Molecular Weight: 9 kDa

Gene ID: 341

UniProt: P02654

Pathways: Apoptosis