SH2B1 antibody

Catalog No. ABIN7464870

This Rabbit Polyclonal antibody specifically detects SH2B1 in WB, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for SH2B1 antibody (ABIN7464870)

Target: SH2B1 (SH2B Adaptor Protein 1 (SH2B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: KO Validated

Product Details anti-SH2B1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SH2B. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: PC-12 , Rat-2 , mouse brain , rat brain , C2C12

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SH2B1

Target: SH2B1 (SH2B Adaptor Protein 1 (SH2B1))

Alternative Name: SH2B adaptor protein 1

Background: SH2B adaptor protein 1 , PSM , SH2B,This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

Molecular Weight: 79 kDa

Gene ID: 25970

UniProt: Q9NRF2