STK3 antibody

Catalog No. ABIN7464946

The Rabbit Polyclonal anti-STK3 antibody is suitable to detect STK3 in samples from Human. It has been validated for WB and IP.

Quick Overview for STK3 antibody (ABIN7464946)

Target: STK3 (serine/threonine Kinase 3 (STK3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-STK3 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human STK3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:10000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: THP-1 , NCI-H929 , STK3 transfected 293T , 293T , A431

Validation: Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for STK3

Target: STK3 (serine/threonine Kinase 3 (STK3))

Alternative Name: serine/threonine kinase 3

Background: Serine/threonine kinase 3 , KRS1 , MST2,Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758], Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM]

Molecular Weight: 56 kDa

Gene ID: 6788

UniProt: Q13188

Pathways: Tube Formation