FVT1 antibody

Catalog No. ABIN7465048

The Rabbit Polyclonal anti-FVT1 antibody is suitable to detect FVT1 in samples from Human. It has been validated for WB.

Quick Overview for FVT1 antibody (ABIN7465048)

Target: FVT1 (KDSR) (3-Ketodihydrosphingosine Reductase (KDSR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FVT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FVT1 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human FVT1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FVT1

Target: FVT1 (KDSR) (3-Ketodihydrosphingosine Reductase (KDSR))

Alternative Name: 3-ketodihydrosphingosine reductase

Background: 3-ketodihydrosphingosine reductase , DHSR , EKVP4 , FVT1 , SDR35C1,The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq]

Molecular Weight: 36 kDa

Gene ID: 2531

UniProt: Q06136