PI4KA antibody

Catalog No. ABIN7465112

This anti-PI4KA antibody is a Rabbit Polyclonal antibody detecting PI4KA in WB, ICC, IF and IHC (p). Suitable for Human.

Quick Overview for PI4KA antibody (ABIN7465112)

Target: PI4KA (Phosphatidylinositol 4-Kinase, Catalytic, alpha (PI4KA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PI4KA antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PI4KA Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PI4 kinase alpha. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.64 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PI4KA

Target: PI4KA (Phosphatidylinositol 4-Kinase, Catalytic, alpha (PI4KA))

Alternative Name: phosphatidylinositol 4-kinase alpha

Background: Phosphatidylinositol 4-kinase alpha , PI4K-ALPHA , PIK4CA , PMGYCHA , pi4K230,This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Molecular Weight: 231 kDa

Gene ID: 5297

UniProt: P42356

Pathways: Inositol Metabolic Process