Spastin antibody

Catalog No. ABIN7465292

This anti-Spastin antibody is a Rabbit Polyclonal antibody detecting Spastin in WB. Suitable for Human.

Quick Overview for Spastin antibody (ABIN7465292)

Target: Spastin (SPAST)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Spastin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Spastin Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Spastin. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , mouse leukocyte

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.35 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Spastin

Target: Spastin (SPAST)

Alternative Name: spastin

Background: Spastin , ADPSP , FSP2 , SPG4,This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4. [provided by RefSeq]

Molecular Weight: 67 kDa

Gene ID: 6683

UniProt: Q9UBP0

Pathways: Microtubule Dynamics, M Phase, Regulation of Cell Size