PAK1IP1 antibody

Catalog No. ABIN7465359

This Rabbit Polyclonal antibody specifically detects PAK1IP1 in WB. It exhibits reactivity toward Human.

Quick Overview for PAK1IP1 antibody (ABIN7465359)

Target: PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK1IP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAK1IP1 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PAK1 interacting protein 1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PAK1IP1

Target: PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

Alternative Name: PAK1 interacting protein 1

Background: PAK1 interacting protein 1 , MAK11 , PIP1 , WDR84 , bA421M1.5 , hPIP1,Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.

Molecular Weight: 44 kDa

Gene ID: 55003

UniProt: Q9NWT1

Pathways: Telomere Maintenance