ANAPC11 antibody (C-Term)
Quick Overview for ANAPC11 antibody (C-Term) (ABIN7465730)
Target
See all ANAPC11 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- C-Term
-
Cross-Reactivity
- Human
-
Purification
- Purified by antigen-affinity chromatography.
-
Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Apc11. The exact sequence is proprietary.
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Comment
-
Positive Control: H1299 , Molt-4
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
-
Preservative
- Thimerosal (Merthiolate)
-
Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))
-
Alternative Name
- anaphase promoting complex subunit 11
-
Background
- Anaphase promoting complex subunit 11 , APC11 , Apc11p , HSPC214,Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
-
Molecular Weight
- 10 kDa
-
Gene ID
- 51529
-
UniProt
- Q9NYG5
Target
-