DCTN3 antibody

Catalog No. ABIN7465763

This anti-DCTN3 antibody is a Rabbit Polyclonal antibody detecting DCTN3 in WB. Suitable for Human.

Quick Overview for DCTN3 antibody (ABIN7465763)

Target: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCTN3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DCTN3 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human DCTN3 Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HCT116

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DCTN3

Target: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Alternative Name: dynactin subunit 3

Background: Dynactin subunit 3 , DCTN-22 , DCTN22,This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq]

Molecular Weight: 21 kDa

Gene ID: 11258

UniProt: O75935

Pathways: M Phase