PLA2G12A antibody

Catalog No. ABIN7465879

The Rabbit Polyclonal anti-PLA2G12A antibody has been validated for WB and IHC (p). It is suitable to detect PLA2G12A in samples from Human.

Quick Overview for PLA2G12A antibody (ABIN7465879)

Target: PLA2G12A (phospholipase A2, Group XIIA (PLA2G12A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G12A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PLA2G12A Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Phospholipase A2 XIIA. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PLA2G12A

Target: PLA2G12A (phospholipase A2, Group XIIA (PLA2G12A))

Alternative Name: phospholipase A2 group XIIA

Background: Phospholipase A2 group XIIA , GXII , PLA2G12 , ROSSY,Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM]

Molecular Weight: 21 kDa

Gene ID: 81579

UniProt: Q9BZM1

Pathways: Inositol Metabolic Process