MARCH2 antibody
Quick Overview for MARCH2 antibody (ABIN7466171)
Target
See all MARCH2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human MARCH2. The exact sequence is proprietary.
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Isotype
- IgG
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anti-Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) (AA 1-176) antibody
MARCH2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 7F3 unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) (AA 146-195) antibodyMARCH2 Reactivity: Human, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) (AA 2-99) antibodyMARCH2 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) (AA 1-176) antibodyMARCH2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) (C-Term) antibodyMARCH2 Reactivity: Human, Rat WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) (Internal Region) antibodyMARCH2 Reactivity: Human, Rat, Mouse, Monkey WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) (AA 191-240) antibodyMARCH2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) (C-Term) antibodyMARCH2 Reactivity: Human, Rat, Mouse, Guinea Pig, Rabbit, Dog WB Host: Rabbit Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) (Middle Region) antibodyMARCH2 Reactivity: Human, Rat, Mouse, Guinea Pig, Rabbit, Dog, Cow, Horse WB Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: HepG2 membrane
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
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Alternative Name
- membrane associated ring-CH-type finger 2
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Background
- Membrane associated ring-CH-type finger 2 , HSPC240 , MARCH-II , RNF172,MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266], Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM]
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Molecular Weight
- 27 kDa
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Gene ID
- 51257
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UniProt
- Q9P0N8
Target
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