MMP24 antibody (N-Term)

Catalog No. ABIN7466240

This anti-MMP24 antibody is a Rabbit Polyclonal antibody detecting MMP24 in WB. Suitable for Human.

Quick Overview for MMP24 antibody (N-Term) (ABIN7466240)

Target: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP24 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMP24 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human MMP24. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: human MMP24-transfected 293T cells , mouse brain , SK-N-SH , IMR32

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MMP24

Target: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Alternative Name: matrix metallopeptidase 24

Background: Matrix metallopeptidase 24 , MMP-24 , MMP25 , MT-MMP 5 , MT-MMP5 , MT5-MMP , MT5MMP , MTMMP5,Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. [provided by RefSeq]

Molecular Weight: 73 kDa

Gene ID: 10893

UniProt: Q9Y5R2