GTPBP3 antibody

Catalog No. ABIN7466322

This Rabbit Polyclonal antibody specifically detects GTPBP3 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for GTPBP3 antibody (ABIN7466322)

Target: GTPBP3 (GTP Binding Protein 3 (Mitochondrial) (GTPBP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTPBP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GTPBP3 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GTPBP3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: IMR32

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GTPBP3

Target: GTPBP3 (GTP Binding Protein 3 (Mitochondrial) (GTPBP3))

Alternative Name: GTP binding protein 3, mitochondrial

Background: GTP binding protein 3, mitochondrial , COXPD23 , GTPBG3 , MSS1 , MTGP1 , THDF1,This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Molecular Weight: 52 kDa

Gene ID: 84705

UniProt: Q969Y2