COG2 antibody (N-Term)

Catalog No. ABIN7466409

This Rabbit Polyclonal antibody specifically detects COG2 in WB. It exhibits reactivity toward Human.

Quick Overview for COG2 antibody (N-Term) (ABIN7466409)

Target: COG2 (Conserved oligomeric Golgi complex subunit 2 (COG2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COG2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COG2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human COG2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for COG2

Target: COG2 (Conserved oligomeric Golgi complex subunit 2 (COG2))

Alternative Name: component of oligomeric golgi complex 2

Background: Component of oligomeric golgi complex 2 , CDG2Q , LDLC,This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.

Molecular Weight: 83 kDa

Gene ID: 22796

UniProt: Q14746