HDC antibody

Catalog No. ABIN7466483

This anti-HDC antibody is a Rabbit Polyclonal antibody detecting HDC in WB. Suitable for Human.

Quick Overview for HDC antibody (ABIN7466483)

Target: HDC (Histidine Decarboxylase (HDC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HDC Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human HDC. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat , Raji , K562 , NCI-H929

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HDC

Target: HDC (Histidine Decarboxylase (HDC))

Alternative Name: histidine decarboxylase

Background: Histidine decarboxylase,The biogenic amine histamine is an important modulator of numerous physiologic processes, including neurotransmission, gastric acid secretion, and smooth muscle tone. The biosynthesis of histamine from histidine is catalyzed by the enzyme L-histidine decarboxylase (HDC, EC 4.1.1.22). This homodimeric enzyme is a pyridoxal phosphate (PLP)-dependent decarboxylase and is highly specific for its histidine substrate.[supplied by OMIM]

Molecular Weight: 74 kDa

Gene ID: 3067

UniProt: P19113