PNPT1 antibody

Catalog No. ABIN7466488

The Mouse Monoclonal anti-PNPT1 antibody has been validated for WB, IP, IF and ICC. It is suitable to detect PNPT1 in samples from Human.

Quick Overview for PNPT1 antibody (ABIN7466488)

Target: PNPT1 (Polyribonucleotide Nucleotidyltransferase 1 (PNPT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PNPT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 4C11

Product Details anti-PNPT1 Antibody

Cross-Reactivity: Human

Purification: Affinity purified by Protein G.

Immunogen: The immunogen used to generate this antibody corresponds to human PNPase.

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat , Raji , K562 , THP-1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PNPT1

Target: PNPT1 (Polyribonucleotide Nucleotidyltransferase 1 (PNPT1))

Alternative Name: polyribonucleotide nucleotidyltransferase 1

Background: Polyribonucleotide nucleotidyltransferase 1 , COXPD13 , DFNB70 , OLD35 , PNPASE , old-35,The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7. [provided by RefSeq, Dec 2012]

Molecular Weight: 86 kDa

Gene ID: 87178

UniProt: Q8TCS8