PCM1 antibody

Catalog No. ABIN7466508

This Rabbit Polyclonal antibody specifically detects PCM1 in WB. It exhibits reactivity toward Human.

Quick Overview for PCM1 antibody (ABIN7466508)

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCM1 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PCM1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat , Raji , NCI-H929

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.95 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PCM1

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Alternative Name: pericentriolar material 1

Background: Pericentriolar material 1 , PTC4 , RET/PCM-1,The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. [provided by RefSeq]

Molecular Weight: 229 kDa

Gene ID: 5108

UniProt: Q15154

Pathways: Stem Cell Maintenance, M Phase, Maintenance of Protein Location