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PCM1 antibody (AA 1-260)
PCM1
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PCM1 Antibody
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Target
See all PCM1 Antibodies
PCM1
(Pericentriolar Material 1 (PCM1))
Binding Specificity
All epitopes for PCM1 antibodies
AA 1-260
Reactivity
All reactivities for PCM1 antibodies
Human
Host
All hosts for PCM1 antibodies
Rabbit
Clonality
All clonalities for PCM1 antibodies
Polyclonal
Conjugate
All conjugates for PCM1 antibodies
This PCM1 antibody is un-conjugated
Application
All applications for PCM1 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Purpose
PCM1 Rabbit pAb
Sequence
MATGGGPFED GMNDQDLPNW SNENVDDRLN NMDWGAQQKK ANRSSEKNKK KFGVESDKRV TNDISPESSP GVGRRRTKTP HTFPHSRYMS QMSVPEQAEL EKLKQRINFS DLDQRSIGSD SQGRATAANN KRQLSENRKP FNFLPMQINT NKSKDASTSP PNRETIGSAQ CKELFASALS NDLLQNCQVS EEDGRGEPAM ESSQIVSRLV QIRDYITKAS SMREDLVEKN ERSANVERLT HLIDHLKEQE KSYMKFLKKI
Cross-Reactivity
Human
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PCM1 (NP_006188.3).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PCM1
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Target
PCM1
(Pericentriolar Material 1 (PCM1))
Alternative Name
PCM1 (PCM1 Products )
Synonyms
wu:fb30g01 antibody, wu:fb94e03 antibody, wu:fe14f07 antibody, PCM1 antibody, ptc4 antibody, pcm-1 antibody, PTC4 antibody, 2600002H09Rik antibody, 9430077F19Rik antibody, C030044G17Rik antibody, PCM-1 antibody, pericentriolar material 1 antibody, pericentriolar material 1 L homeolog antibody, pcm1 antibody, PCM1 antibody, Pcm1 antibody, pcm1.L antibody
Background
The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.,PCM1,PTC4,RET/PCM-1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,PCM1
Molecular Weight
59kDa/222kDa/228kDa
Gene ID
5108
UniProt
Q15154
Pathways
Stem Cell Maintenance , M Phase , Maintenance of Protein Location
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