DARS2 antibody

Catalog No. ABIN7466617

The Rabbit Polyclonal anti-DARS2 antibody is suitable to detect DARS2 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for DARS2 antibody (ABIN7466617)

Target: DARS2 (Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DARS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DARS2 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human AspRS. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: MCF-7

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DARS2

Target: DARS2 (Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2))

Alternative Name: aspartyl-tRNA synthetase 2, mitochondrial

Background: Aspartyl-tRNA synthetase 2, mitochondrial , ASPRS , LBSL , MT-ASPRS,The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL). [provided by RefSeq]

Molecular Weight: 74 kDa

Gene ID: 55157

UniProt: Q6PI48