PCDHGC5 antibody

Catalog No. ABIN7466632

The Rabbit Polyclonal anti-PCDHGC5 antibody has been validated for WB. It is suitable to detect PCDHGC5 in samples from Human.

Quick Overview for PCDHGC5 antibody (ABIN7466632)

Target: PCDHGC5 (Protocadherin gamma Subfamily C, 5 (PCDHGC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHGC5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCDHGC5 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PCDHGC5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: MCF-7

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.75 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PCDHGC5

Target: PCDHGC5 (Protocadherin gamma Subfamily C, 5 (PCDHGC5))

Alternative Name: protocadherin gamma subfamily C, 5

Background: Protocadherin gamma subfamily C, 5 , PCDH-GAMMA-C5,This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq]

Molecular Weight: 102 kDa

Gene ID: 56097

UniProt: Q9Y5F6