Endonuclease G antibody
Quick Overview for Endonuclease G antibody (ABIN7466766)
Target
See all Endonuclease G (ENDOG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human EndoG. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: Mouse brain , A549
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.72 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Endonuclease G (ENDOG)
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Alternative Name
- endonuclease G
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Background
- Endonuclease G,The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq]
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Molecular Weight
- 33 kDa
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Gene ID
- 2021
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UniProt
- Q14249
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Pathways
- Apoptosis
Target
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