Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2) (C-Term) antibody

Catalog No. ABIN7466818

The Rabbit Polyclonal anti- antibody has been validated for WB. It is suitable to detect in samples from Human.

Quick Overview for Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2) (C-Term) antibody (ABIN7466818)

Target: Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: C-Term

Cross-Reactivity: Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human RASGRF2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse brain , rat brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details

Target: Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2)

Alternative Name: Ras protein specific guanine nucleotide releasing factor 2

Background: Ras protein specific guanine nucleotide releasing factor 2 , GRF2 , RAS-GRF2,RAS (MIM 190020) GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound form into the active form.[supplied by OMIM]

Molecular Weight: 141 kDa

Gene ID: 5924

UniProt: O14827

Pathways: Neurotrophin Signaling Pathway