ITPKA antibody

Catalog No. ABIN7466820

This Rabbit Polyclonal antibody specifically detects ITPKA in WB. It exhibits reactivity toward Human.

Quick Overview for ITPKA antibody (ABIN7466820)

Target: ITPKA (Inositol-Trisphosphate 3-Kinase A (ITPKA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPKA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ITPKA Antibody

Cross-Reactivity: Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human IP3KA. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse brain , rat brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ITPKA

Target: ITPKA (Inositol-Trisphosphate 3-Kinase A (ITPKA))

Alternative Name: inositol-trisphosphate 3-kinase A

Background: Inositol-trisphosphate 3-kinase A , IP3-3KA , IP3KA,Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011]

Molecular Weight: 51 kDa

Gene ID: 3706

UniProt: P23677