USP47 antibody

Catalog No. ABIN7466842

The Rabbit Polyclonal anti-USP47 antibody has been validated for WB and IHC (p). It is suitable to detect USP47 in samples from Human.

Quick Overview for USP47 antibody (ABIN7466842)

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP47 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-USP47 Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human USP47. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse brain , U87-MG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.54 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for USP47

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Alternative Name: ubiquitin specific peptidase 47

Background: Ubiquitin specific peptidase 47 , TRFP,Putative ubiquitin-specific-processing protease that regulates cell growth and survival. Probably regulates CDC25A expression at a transcriptional level. May be catalytically inactive although it seems to have kept all necessary active site residues.

Molecular Weight: 157 kDa

Gene ID: 55031

UniProt: Q96K76

Pathways: Negative Regulation of intrinsic apoptotic Signaling