USP47 antibody (AA 588-620)

Catalog No. ABIN6242880

Product Details anti-USP47 Antibody

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Binding Specificity: AA 588-620

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP47 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This USP47 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 588-620 amino acids from the Central region of human USP47.

Clone: RB53787

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for USP47

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Alternative Name: USP47 (USP47 Products)

Synonyms: USP47 antibody, zgc:165650 antibody, TRFP antibody, 4930502N04Rik antibody, A630020C16Rik antibody, ubiquitin specific peptidase 47 antibody, ubiquitin carboxyl-terminal hydrolase 47 antibody, ubiquitin specific peptidase 47 S homeolog antibody, Usp47 antibody, USP47 antibody, usp47 antibody, LOC100639726 antibody, usp47.S antibody

Background: Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulates CDC25A expression at a transcriptional level.

Molecular Weight: 157311

UniProt: Q96K76

Pathways: Negative Regulation of intrinsic apoptotic Signaling