TPR antibody (C-Term)

Catalog No. ABIN7466907

This Rabbit Polyclonal antibody specifically detects TPR in WB, ICC and IF. It exhibits reactivity toward Human.

Quick Overview for TPR antibody (C-Term) (ABIN7466907)

Target: TPR (Nucleoprotein TPR (TPR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPR antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-TPR Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TPR. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse lung

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.37 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TPR

Target: TPR (Nucleoprotein TPR (TPR))

Alternative Name: translocated promoter region, nuclear basket protein

Background: Translocated promoter region, nuclear basket protein,This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq]

Molecular Weight: 267 kDa

Gene ID: 7175

UniProt: P12270