TCAP antibody

Catalog No. ABIN7466910

This Rabbit Polyclonal antibody specifically detects TCAP in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for TCAP antibody (ABIN7466910)

Target: TCAP (Titin-Cap (Telethonin) (TCAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TCAP Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human Telethonin Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse muscle

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TCAP

Target: TCAP (Titin-Cap (Telethonin) (TCAP))

Alternative Name: titin-cap

Background: Titin-cap , CMD1N , CMH25 , LGMD2G , LGMDR7 , T-cap , TELE , telethonin,Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008]

Molecular Weight: 19 kDa

Gene ID: 8557

UniProt: O15273