LMX1B antibody

Catalog No. ABIN7466923

The Rabbit Polyclonal anti-LMX1B antibody has been validated for WB and IHC (fro). It is suitable to detect LMX1B in samples from Human.

Quick Overview for LMX1B antibody (ABIN7466923)

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMX1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-LMX1B Antibody

Cross-Reactivity: Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human LMX1B. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse skeletal muscle

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for LMX1B

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Alternative Name: LIM homeobox transcription factor 1 beta

Background: LIM homeobox transcription factor 1 beta , LMX1.2 , NPS1,This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molecular Weight: 42 kDa

Gene ID: 4010

UniProt: O60663

Pathways: Dopaminergic Neurogenesis