KCNJ9 antibody (AA 61-160) (HRP)

Catalog No. ABIN719765

The Rabbit Polyclonal anti-KCNJ9 antibody is suitable to detect KCNJ9 in samples from Human. It has been validated for WB, ELISA, IHC (p) and IHC (fro).

Quick Overview for KCNJ9 antibody (AA 61-160) (HRP) (ABIN719765)

Target: KCNJ9 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 9 (KCNJ9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ9 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-KCNJ9 Antibody (HRP)

Binding Specificity: AA 61-160

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GIRK3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KCNJ9

Target: KCNJ9 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 9 (KCNJ9))

Alternative Name: GIRK3

Background:

Synonyms: G protein activated inward rectier potassium channel 3, G protein coupled inward rectier potassium channel, GIRK3, Inwardly rectier K+ channel Kir3.3, Inwardly rectier K+ channel KIR3.3, KIR3.3, Potassium channel inwardly rectying subfamily J member 9, Potassium inwardly rectying channel subfamily J member 9, Potassium inwardly rectying channel subfamily J9.

Background: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Gene ID: 3760